Updated

Here's an updated look at a Jerome Gambit variant that still holds a lot of poison for White.

In raw position comparisons, The Database has 9244 games after 1.e4 e5 2.Nf3 Nc6 3.Bc4 Bc5 4.Bxf7+ where White scores 44%; while it has 1780 games after 1.e4 e5 2.Nf3 Nc6 3.Nc3 Bc5 4.Bc4 Nf6 5.Bxf7+, where White scores 38%.

Ryndael - emranhamid
standard, FICS, 2012

1.e4 e5 2.Nf3 Nc6 3.Nc3 Bc5 4.Bc4 Nf6 5.Bxf7+ 

The Italian Four Knights Jerome Gambit.

5...Kxf7 6.Nxe5+ Nxe5 7.d4 Bd6 8.f4

This line was investigated in "Attitude" and "Where Do Ideas Come From?" Parts 1, 2, 3, 4, 5 and 6. 

I was surprised to see that Houdini 2, at 20 ply depth, considers it about equivalent to 8.dxe5.

Black's next move is new, however.

8...Nc4 9.e5 Bb4 10.0-0 Bxc3 11.bxc3 Ne4 

12.f5

A slight improvement over 12.Qd3 d5 13.f5 in Rijndael - creamen, FICS, 2011, (0-1, 28).

12...Rf8 13.Rf4 d5 14.Qh5+ Kg8

White now throws everything into a frantic attack, but there is little hope.

15.Rxe4 dxe4 16.Bg5 Qd5 17.f6 gxf6 18.Rf1 Nxe5 19.Bxf6 Nf3+ 20.Rxf3 Qxh5 21.Rg3+ Kf7 White resigned

graphic by Jeff Bucchino, the Wizard of Draws