One Slip

It is true that the Jerome Gambit (1.e4 e5 2.Nf3 Nc6 3.Bc4 Bc5 4.Bxf7+) has a number of refutations, but it is necessary for Black to chose one and play it. Treating the opening as toothless can lead to unhappy surprises and poor outcomes.

calchess - Baron wd von Blanc
Jerome Gambit Thematic Tournament, ChessWorld, 2010

1.e4 e5 2.Nf3 Nc6 3.Bc4 Bc5 4.Bxf7+

4...Kxf7 5.Nc3 Nf6

Here we see the link betwen the "modern" variations of the Jerome Gambit (those without 5.Nxe5) and the Italian Four Knights Jerome Gambit, which reaches the same position from a different move order: 1.e4 e5 2.Nf3 Nc6 3.Bc4 Nf6 4.Nc3 Bc5 5.Bxf7+ Kxf7.

In this game, in "modern" fashion, White does not follow with the usual Italian Four Knights Jerome Gambit 6.Nxe5.

6.a3 d5

Thematic and good.

7.exd5 Nxd5 8.Ne4 Bb6

Black is doing well: he has an extra piece and he has the better development. It should take him a couple of moves to castle-by-hand, and then he will be comfortable as well.

Instead, he is lulled by White's calm play, and his next move gives up the advantage.

9.0-0 Bg4

10.Nfg5+ Kg8 11.Qxg4 Nf6

And this "defensive" move loses the game.

12.Qe6+ Kf8 13.Qf7 checkmate